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Lion's Mane Capsules 
Lion's Mane CapsulesFrom $20.95From $20.95 -
Turkey Tail Capsules 
Turkey Tail CapsulesFrom $20.95From $20.95 -
Stamets 7® Capsules 
Stamets 7® CapsulesFrom $20.95From $20.95 -
MycoBotanicals® Brain* Capsules 
MycoBotanicals® Brain* Capsules$31.95$31.95 -
Lion's Mane Powder 
Lion's Mane PowderFrom $31.95From $31.95 -
Reishi Capsules 
Reishi CapsulesFrom $20.95From $20.95 -
Lion's Mane Extract 
Lion's Mane ExtractFrom $20.95From $20.95 -
Stamets 7® Powder 
Stamets 7® PowderFrom $31.95From $31.95
Welcome to Host Defense Mushrooms! Founded by Paul Stamets, our mushroom mycelium and fruit bodies grown on our certified organic farm in Washington State are non-GMO, vegan, and gluten-free. We base our formulations on scientifically proven data to ensure quality and safety, which is why we are the best selling mushroom supplement brand in the U.S.ꝉ
A product of Fungi Perfecti, LLC. Building Better Health Since 1980.*
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Relax, Recharge and Carry on*
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MycoBenefits™ Mood* Capsules 
MycoBenefits™ Mood* Capsules$29.95$29.95 -
MycoBenefits™ Sleep* Capsules 
MycoBenefits™ Sleep* Capsules$29.95$29.95 -
Reishi Capsules
Reishi CapsulesFrom $20.95From $20.95 -
MycoBotanicals® Stress Decompress®* Capsules 
MycoBotanicals® Stress Decompress®* Capsules$31.95$31.95 -
Reishi Powder 
Reishi Powder$31.95$31.95 -
Reishi Extract 
Reishi ExtractFrom $20.95From $20.95 -
CordyChi® Capsules 
CordyChi® CapsulesFrom $20.95From $20.95 -
CordyChi® Extract 
CordyChi® ExtractFrom $20.95From $20.95
Why Host Defense?
Founded by Paul Stamets
Pioneered by world-renowned mycologist Paul Stamets to connect people with the power of fungi.
Powered by Mushroom Mycelium
The foundation of every Host Defense supplement and our mission.
Innovative Research & Development
Our in-house R&D team drives groundbreaking research in fungi and wellness.
Climate Positive Commitment
We offset 110 percent of our emissions to create a net positive impact for people and planet.
Exceptional Customer Support
Our friendly, knowledgeable team is here to help at every step.
Self-Care Made Simple
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MycoBenefits™ Focus* Capsules 
MycoBenefits™ Focus* Capsules$29.95$29.95 -
MycoBenefits™ Mood* Capsules
MycoBenefits™ Mood* Capsules$29.95$29.95 -
MycoBenefits™ Beauty Capsules 
MycoBenefits™ Beauty Capsules$29.95$29.95 -
MycoBenefits™ Sleep* Capsules
MycoBenefits™ Sleep* Capsules$29.95$29.95
