Paul DustyHost Defense emerged from the fusion of skill sets from two experts: Paul Stamets and C. Dusty Yao. Paul's long time expertise in the taxonomy and cultivation of mushrooms perfectly matched C. Dusty Yao's years of making herbal extracts. The marriage - literally - of these two experts gave rise to the Host Defense products you enjoy today. Their shared passion for exploring the natural world, from thousands of hours of hiking (and laughing) through the old growth forest, and their combined ideas created the wellspring that gave birth to the  Host Defense product lines that continue today.

Join us as we continue to walk this path of exploration and healing, bridging modern science with ancient traditions. We honor and share the wisdom of nature. Host Defense is more than a product line: we are on a myco-mission to spread the power of  mushrooms supporting healthy lifestyles.

Your help on this mission is deeply appreciated. We can not succeed without you!

Respectfully,  Paul Stamets & C. Dusty Yao

Why Choose Host Defense Mushrooms

  • Host Defense grown in the usaGrown in the USA

    • Near the Olympic Rainforest, USA
    • Highest quality lab & growing environments
    • Highest quality manufacturing methods
    • No co-mingling or adulteration
    • Purity testing batch to batch

  • Host Defense chain of custodyMaintain Chain of Custody

    Paul Stamets and his skilled team grow every single mushroom in every product. From the Forest, to Our Farm, to You.

    There is no other mushroom supplement company that has such complete control over their raw materials.

  • Host Defense sustainably cultivated
    Sustainably Cultivated

    When sourcing mushrooms from the pristine Olympic rainforest, our team leaves the habitat and original mushroom intact and undisturbed. Only a small sample is required and taken for growing in the laboratories at the farm. Host Defense® methods protect the native habitat.

    Our vast culture library of rare and endangered mushroom species has been called a national treasure.

  • Host Defense ceritified organic
    Certified Organic

    Host Defense is a Certified Organic food producer and processor. Our organic certificates are always available upon request. We are the best-documented and longestcertified organic mushroom company in the U.S.1

    Supervision by Paul Stamets, D.Sc. - Paul Stamets is the world leader in functional food mushroom research - whose books are recognized as the standards of the mushroom cultivation industry.2

  • Host Defense genetic matchPreserved Genetic Integrity

    Host Defense® mushrooms are genetic matches to species found in the wild. We are able to ensure this integrity by following a method developed by Paul called Certified P Value.® P Value® is a scientific system of measuring the generational age of each species to preserve genetic strength, and is key to providing fungal strains with the greatest efficacy and vitality. The higher P Value gets, strains degenerate and die out. Utilizing extremely low P Value, Host Defense uses the “original file” to produce mushrooms of exceptional genetic strength and integrity, close to their wild origins which means the active constituents are at very high levels. 

  • Host Defense peak efficacyPeak Performance

    Each mushroom species has a narrow window when active constituents are at their highest volume. With over 40 years of experience and knowledge, Paul knows the precise harvest time for each species for maximum activity and efficacy. 

    At their optimal rate of growth, the mushroom-forming mycelium are flash-frozen, capturing a full spectrum of constituents at peak performance.

  • Host Defense prebioticsPrebiotics for the Microbiome

    Our products contain the active enzymes fungi have evolved to digest plants. What are the specific prebiotic compounds present in our products? Hundreds of novel enzymes are being secreted by the mycelium to break down plants. We eat plants, so do fungi. These extracellular digestive enzymes (cellulases, laccases, betaglucanases, mannanases, etc.) are in the extracts and capsules. This is a great advantage of freeze drying. We capture those enzymes which would otherwise be lost via most other drying methods. 

  • Host Defense mushroom cycle
    Proper Mushroom Life Cycle

    The mushroom life cycle consists of mycelium, fruiting bodies, and spores. The mycelium is the immune system of the mushroom.™ The fruiting body is the reproductive stage. Spores represent seeds for regeneration and are in every Host Defense® product that contains fruitbodies. Depending on the species and the intended use, we utilize a unique combination of the life stages. For example, our Cordyceps capsules contain mycelium. MyCommunity™ Extract contains mycelium and both Maitake and Reishi fruitbodies.

  • Host Defense in vitroClinical & In Vitro Studies

    Host Defense® Turkey Tail was chosen for a NIH (National Institutes of Health) study for supporting immune system health. 

    Clinical studies show Host Defense® Chaga is superior in antioxidant effects, protecting DNA from free radicals (which cause oxidative stress damage). 

    Of more than 200,000 samples submitted, Host Defense® Agarikon demonstrated the most activity of all natural products in the BioShield BioDefense Program administered by the Department of Defense and NIH. In fact, our mushrooms were the only products to show such extraordinary activity.*

  • Host Defense recommended by expertsRecommended by Experts

    Host Defense® products are chosen by physicians, naturopaths and other practitioners for efficacy with their patients.

    Host Defense®, owned by mycologist and author Paul Stamets, is the best all around source for immunesupporting mushroom products and information.*” - Andrew Weil, M.D. 

1 No capsules available to the industry are certified organic: thus we cannot claim 100% organic, although our ingredients and processes are 100% certified organic.

2 The Mushroom Cultivator; Growing Gourmet & Medicinal Mushrooms; Mycelium Running: How Mushrooms Can Help Save the World, and MycoMedicinals, An Informational Guide to Medicinal Mushrooms.

* These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

For educational purposes only. © 2013 Paul E. Stamets and Fungi Perfecti, LLC, All rights reserved.


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PO BOX 7634 • OLYMPIA, WA 98507 • USA  •  HOURS OF OPERATION: Monday–Friday 8:30am–4:30pm PST
Toll-Free: (877) 504-MYCO (6926) • Phone: (360) 427-4561  •  Fax: (360) 426-6584 • email: This email address is being protected from spambots. You need JavaScript enabled to view it.

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. For educational purposes only.
+Your purchase helps support research to protect bees from colony collapse as well as rare species of mushrooms dwelling in old growth forests.
© 2016 Paul E. Stamets and Fungi Perfecti, LLC, All rights reserved.

Please Note: the contact information listed above is for wholesale customers only. For retail orders and information, please contact Fungi Perfecti
All portions of this site © 2016, all rights reserved, unless otherwise noted.